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4-FPD(4-氟-戊基卡西酮)

購買 4-fpd
購買 4-fpd
4-FPD

4-FPD Buy | Wholesale 4-FPD | 4 fluoro pentedrone buy

4-FPD or 4F-pentedrone buy , 4-fluoro-pentedrone, is a new designer drug for chemical research, is a Hexen analogue and has all its properties.
4-FPD buy and pentylone are both synthetic cathinones, a class of psychoactive substances that have emerged as novel psychoactive substances (NPS). Structurally, they are β-keto amphetamine analogues. While both are recognized for their stimulant properties, their specific interactions with monoamine transporters—the dopamine transporter (DAT), the serotonin transporter (SERT), and the norepinephrine transporter (NET)—dictate their unique pharmacological profiles and psychoactive effects. Understanding these differences is crucial. 4-FPD was synthesized in a modern chemical laboratory in compliance with all standards.

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4-FPD 10g 100 $ 加入購物車

4-FPD 100g 400 $ 加入購物車 免費運送!

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4-FPD 10 kg 8300 $ 加入購物車 免費運送!

4-FPD is a drug designed for research and forensic applications. Toxicological and physiological properties of 4-FPD have not been studied. Pentylone has been characterized as a non-selective monoamine transporter inhibitor and a serotonin-releasing agent. In contrast, detailed pharmacological data for 4-FPD is less prevalent in the scientific literature. However, its structural similarity to pentedrone, a known norepinephrine-dopamine reuptake inhibitor (NDRI), allows for informed inferences about its likely mechanism of action. This guide will present the available quantitative data for pentylone and utilize data for pentedrone as a proxy for 4-FPD, with the clear acknowledgment of this substitution due to the current limitations in published research on 4-FPD.

4 fluoro pentedrone Comparative Analysis of Effects

Pentylone exhibits a profile of a relatively non-selective monoamine transporter inhibitor, with a notable potency at the norepinephrine transporter. Its classification as a serotonin-releasing
agent suggests a mechanism of action that goes beyond simple reuptake blockade, which may contribute to its reported empathogenic effects. The lower DAT/SERT ratio of pentylone compared to pentedrone indicates a more balanced action between the dopaminergic and serotonergic systems.
4-FPD, based on the data for its structural analogue pentedrone, is predicted to be a more selective norepinephrine-dopamine reuptake inhibitor (NDRI).[1] The significantly higher IC50 value for SERT suggests a much weaker interaction with the serotonin transporter compared to pentylone. This pharmacological profile would likely result in predominantly stimulant effects, with less of the serotonergic-mediated effects observed with pentylone. The addition of a fluorine atom to the phenyl ring in 4-FPD may influence its potency and selectivity, a common strategy in medicinal chemistry to modulate pharmacokinetic and pharmacodynamic properties. However, without direct experimental data, the precise impact of this substitution remains speculative.

Signaling Pathways and Experimental Workflows

To visually represent the mechanisms of action and experimental procedures discussed, the following diagrams are provided in DOT language for Graphviz.

Monoamine Transporter Inhibition

The following diagram illustrates the primary mechanism of action for both pentylone and,presumably, 4-FPD as monoamine transporter inhibitors

Storage conditions: in a cool, dry place.
儲存期限:在適當的儲存條件下可達 2 年。.

非供人類食用.

4-FPD
4-FPD

 

 

 

 

 

 

同義詞 4-FPD

4F-pentedrone

4-fluoro-pentedrone

國際純化學與應用化學聯合會 2-fluoromethyl-1-phenylpentan-1-one
公式 C13H18FNO
分子量
CAS 879669-95-1
外觀 結晶,粉末
純度 ≥ 99 %

 

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Pentedrone (也稱為 α-methylaminovalerophenone) is a stimulant 的 cathinone class that has been sold as a 設計毒品 and has been found since 2010 as an ingredient in a number of “bath salt” mixes sold as legal highs.

藥理學

Pentedrone acts as a norepinephrine-dopamine reuptake inhibitor (NDRI) without inducing monoamine release, a similar mechanism of action to methylphenidate. Its IC50Tooltip half-maximal inhibitory concentration values for inhibition of monoamine reuptake have been reported to be 610 nM for norepinephrine, 2,500 μM for dopamine, and 135,000 μM for serotonin.In rodents, pentedrone has been found to produce conditioned place preference (CPP), to be self-administered, and to dose-dependently stimulate locomotor activity.Hence, pentedrone shows psychostimulant-like and reinforcing effects in animals.

Side effects 

Pentedrone has been linked to at least one death where it was combined with α-PVP and caused heart failure. 

Where to Buy 4-fluoro Pentedrone (hydrochloride) | 4-fpd buy

4-fluoro Pentedrone (hydrochloride) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic …

Application Scenarios for Pentedrone (CAS 879722-57-3) | 4-FPD buy Scenarios

Reference Standard for Selective Catecholaminergic Pathway Studies

For neuropharmacological research models where isolating the effects of dopamine and norepinephrine reuptake is critical, Pentedrone serves as an ideal tool. Its high DAT/SERT selectivity ratio ensures minimal off-target serotonergic activity, which is a known confounding variable with analogs like Methylone.

Behavioral Models Requiring Sustained, Long-Duration Stimulant Effects

In experimental paradigms such as conditioned place preference or drug discrimination that require a prolonged and stable drug effect, Pentedrone’s 67-150% longer duration of action compared to Methylone and Pentylone simplifies protocols by reducing the need for multiple administrations.

Mechanistic Control for Differentiating Reuptake Inhibition vs. Release

When investigating the neurochemical differences between cathinone classes, Pentedrone is the appropriate choice as a non-releasing reuptake inhibitor to contrast with monoamine-releasing agents like Mephedrone. This allows for direct assessment of how these distinct mechanisms contribute to cellular and behavioral outcomes.

Certified Reference Material for Forensic and Toxicological Analysis

Given its unique pharmacological profile (selectivity, duration, mechanism) and metabolic pathway, high-purity Pentedrone is essential for developing and validating analytical methods to unambiguously differentiate it from a growing list of structurally similar cathinone analogs in seized materials or biological samples.

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