Quetiapine

Quetiapine (trade name Seroquel) is an antipsychotic drug for the treatment of schizophrenia, depression and bipolar disorder, with sedative properties. It was developed in 1985 and approved for medical use and is more effective than Haloperidol.

Quetiapine has been used as an adjunct in the treatment of Tourette syndrome.

Quetiapine is the most widely used drug for the treatment of psychosis in Parkinson’s disease, due to the low probability of side effects.

There are side effects with improper use of the drug, such as dizziness, dry mouth, drowsiness or excessive high blood pressure, high heart rate, constipation, vomiting, decreased appetite, insomnia, fatigue.

Quetiapine can cause an increase in body weight when used, this is due to its effect on histamine H1 receptors and 5-HT2C receptors.

This drug, like other antipsychotics, can lower the threshold of seizures. When changing the drug, the dosage should be carefully and gradually reduced in order to avoid withdrawal syndrome as much as possible, which may include symptoms such as anxiety, insomnia, excessive sweating, nausea, vomiting and loss of appetite.

Overdose of the drug leads only to sedation, hypotension and tachycardia in most cases.

Quetiapine is an antagonist of 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT3, 5-HT6, 5-HT7, α1A, α1B, α2A, α2B, α2C, NMDA(PCP) and some other receptors, such as Dopamine D1, D2, D3, D4, and D5, Histamine H1.

When taking quetiapine, the peak level of quetiapine occurs approximately 1.5 hours after administration, and the half-life of quetiapine is 6 or 7 hours.

Chemical structure.

Quetiapine is a tetracyclic compound and structurally close to clozapine. A drug with dibenzothiazepinone is synthesized, nucleophilic substitution is used to introduce the side chain.

Quetiapine is sold strictly by prescription in the USA, Canada, Great Britain and Austria.

You can buy Quetiapine online in our store right now.

Quetiapine is a new designer drug designed for research and forensics.

Toxicological and physiological properties of Quetiapine have not been studied.

Quetiapine synthesized in the modern laboratory in compliance with all standards.

 

 

 

 

 

 

 

Synonyms	Quetiapine Seroquel Quetiapine fumarate Norsic
IUPAC	2-[2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethoxy]ethanol
Formula	C21H25N3O2S
Molecular weight	383.5
CAS	111974-69-7
Appearance	Powder
Purity	≥ 98 %

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