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Diclazepam

Diclazepam
Buy Diclazepam
Diclazepam

Buy Diclazepam online |Wholesale Diclazepam

Buy Diclazepam in Chemsaxis online. Diclazepam, another name for 2-chlordiazepam, is a new development of a benzodiazepine designer drug series, acting as a sedative and a good antidepressant. It tends to enhance the effect of alcohol and other sedatives. Diclazepam is the newest development on the market of designer drugs, which has legal status in many countries. Diclazepam is produced in modern chemical industry with compliance with all standards.

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Diclazepam 10g 169 $ Añadir al carrito

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Buy Diclazepam in Chemsaxis online.

Diclazepam is a new designer drug designed for research and forensic applications.

Toxicological and physiological properties of Diclazepam have not been studied.

Condiciones de almacenamiento: en un lugar fresco y seco.
Tiempo de almacenamiento: hasta 2 años sujeto a las condiciones de almacenamiento adecuadas.

We ship the product in a double sealed bag which can be resealed. Another container is recommended sealing from outside air.

No apto para consumo humano.

Diclazepam
Diclazepam
Sinónimos Diclazepam
2-Chlorodiazepam
IUPAC 7-chloro-5-(2-chlorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-on
Fórmula C16H12Cl2N2O
Peso molecular 319.185 g/mol
CAS 2894-68-0
Apariencia Polvo
Pureza

 

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Plazo de entrega de 3 a 4 días laborables.
Velocidad de entrega 100% en toda Europa.

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diclazepam is not currently marketed as a medication, but rather sold online as a research chemical. its potency has not been systematically tested in humans, but its closest relatives and two main metabolites are lormetazepam with a potency value of x10-12 of delorazepam which is roughly x10 the potency of diazepam.

users should note that the sudden discontinuation of benzodiazepines can be potentially dangerous or life-threatening for individuals using regularly for extended periods of time, sometimes resulting in seizures or death. it is highly recommended to taper one’s dose by gradually lowering the amount taken each day over a prolonged period of time rather than stopping use abruptly, as this can lead to crippling, potentially life-threatening withdrawal symptoms.

Chemistry

composition

diclazepam is a drug of the benzodiazepine class. benzodiazepine drugs contain a benzene ring fused to a diazepine ring, which is a seven-membered ring with the two nitrogen constituents located at r1 and r4. at r1, diclazepam is substituted with methyl group. further, the benzodiazepine ring is bonded at r5 to a 2-chlorinated phenyl ring. r7 of the benzyl ring is also substituted with a chlorine group. diclazepam also contains an oxygen group double bonded to r2 of its diazepine ring to form a ketone. this oxygen substitution at r2 is shared with other benzodiazepine drugs with the suffix -azepam.

pharmacology

benzodiazepines produce a variety of effects by binding to the benzodiazepine receptor site and magnifying the efficiency and effects of the neurotransmitter gamma aminobutyric acid (gaba) by acting on its receptors. as this site is the most prolific inhibitory receptor set within the brain, its modulation results in the sedating (or calming effects) of diclazepam on the nervous system.

the anticonvulsant properties of benzodiazepines may be, in part or entirely, due to binding to voltage-dependent sodium channels rather than benzodiazepine receptors.

Metabolism

Metabolism of this compound has been assessed, revealing diclazepam has an approximate elimination half-life of 42 hours and undergoes N-demethylation to delorazepam, which can be detected in urine for 6 days following administration of the parent compound. Other metabolites detected were lorazepam and lormetazepam which were detectable in urine for 19 and 11 days, respectively, indicating hydroxylation by cytochrome P450 enzymes occurring concurrently with N-demethylation.
Formal Name : 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one 
CAS Number : 2894-68-0 
Molecular Formula : C16H12Cl2N2O 
Formula Weight :  319.2 
Purity :  â‰¥98% 
Formulation : A neat solid 
Solubility  (Learn about Variance in Solubility) 
DMF: 30 mg/ml
DMSO: 30 mg/ml
DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
Ethanol: 10 mg/ml

Abstract
Background: Recently the number of new psychoactive substances have significantly increased, becoming popular among experienced users of designer drugs. A significant group includes benzodiazepine derivatives, which have not been introduced as medications but are abused by people experimenting with new and classical psychoactive substances.
Case presentation: The aim of this paper was to present the case of a clonazolam ingestion by a person who was not habituated to benzodiazepines. The intake caused only prolonged coma, decreased muscle tone, and deep tendon reflexes without any other concomitant toxicity and cardio-respiratory failure.
Conclusions: Clonazolam concentrations in patient’s blood, measured three times were 0.077 mg/L, 0.015 mg/L, 0.009 mg/L after 4, 8 and 12 h, respectively. Clonazolam’s human toxicity has not been well established, so any case of poisoning should be closely monitored.

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